Abstract
A new method for the determination of kanamycin (KANA) was developed based on enhancing the fluorescence intensity of thioglycollic acid (TGA) modified CdTe/CdSe quantum dots (QDs) by KANA. Under optimal conditions, the fluorescence intensity was proportional to the concentration of KANA between 1.0 to 10.0 μg mL-1 with a correlation coefficient of 0.9981
and a detection limit of 25 ng mL1. Moreover, the proposed method was successfully applied to the determination of KANA
in the pharmaceutical formulation and human serum, and the results w ere satisfactory. In addition, the reaction mechanism
was also discussed in detail..
Keywords
CdTe/CdSe Quantum dots Kanamycin Fluorescence enhancement Determination.
Citation
YONGQIANG MAO, NA LI, YE HAN, ZHIJIANG ZHOU, CdTe/CdSe quantum dots as a fluorescent probe for kanamycin determination in the pharmaceutical formulation and human serum, Optoelectronics and Advanced Materials - Rapid Communications, 6, 9-10, September-October 2012, pp.879-882 (2012).
Submitted at: Jan. 30, 2012
Accepted at: Sept. 20, 2012