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Crystal powder silver nanoparticles green synthesized, characterization, antibacterial and cytotoxicity effects

MANAL A. AWAD1,* , AWATIF A. HENDI2, KHALID M. O. ORTASHI3, RABAB A. EL DIB4,5

Affiliation

  1. King Abdullah Institute for Nanotechnology, King Saud University, KSA
  2. Physics Department, Faculty of Science, King Saud University, KSA
  3. Department of Chemical Engineering, King Saud University, KSA
  4. Pharmacognosy Department, College of Pharmacy, King Saud University, KSA
  5. Department of Pharmacognosy, College of Pharmacy, Helwan University, Helwan 11795, Egypt

Abstract

We described a simple, cost effective, non-toxic and environmental friendly green- chemistry reduction method to synthesized crystal nano silver (AgNPs) powder using CTAB and orange peel extract as reducing agent. The green – reduced crystal nano silver powder was characterized using XRD analysis, Zeta sizer, Scanning Electron Microscopy (SEM) equipped with Energy Dispersive Spectroscopy (EDS) in addition to Transmission Electron Microscopy (TEM). The synthesized crystal nano silver showed promising antibacterial activity against gram negative (Escherichia coli) and gram positive (staphylococcus aureus and Streptococcus). The present study demonstrates the efficiency of synthesized nano silver as a cytotoxic agent against MCF-7 breast cancer cell line and HepG2 liver hepatocellular cancer cell line using by MTT assay. Thus, the synthesized crystal nano silver can be used as a wide range therapeutic agent against bacteria and cancer..

Keywords

Green Synthesis, Nano silver, Crystal Powder, Characterization, MTT, cytotoxicity and antibacterial.

Citation

MANAL A. AWAD, AWATIF A. HENDI, KHALID M. O. ORTASHI, RABAB A. EL DIB, Crystal powder silver nanoparticles green synthesized, characterization, antibacterial and cytotoxicity effects, Optoelectronics and Advanced Materials - Rapid Communications, 9, 11-12, November-December 2015, pp.1520-1526 (2015).

Submitted at: Sept. 27, 2015

Accepted at: Oct. 28, 2015