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Electrochemotherapy of skin cancer treatment results estimated by in vivo autofluorescence measurements

BILIANA NIKOLOVA1,* , EKATERINA BORISOVA2, EKATERINA PEYCHEVA3, LATCHEZAR AVRAMOV2, IANA TSONEVA1

Affiliation

  1. Institute of Biophysics and Biomedical Engineering, Bulgarian Academy of Sciences, Sofia, Bulgaria, Acad. G. Bonchev str., Bl.21, 1110 Sofia, Bulgaria
  2. Institute of Electronics, Bulgarian Academy of Sciences, 72, Tsarigradsko chaussee Blvd., 1784 Sofia, Bulgaria
  3. Specialized Hospital for Active Treatment of Oncology, Plovdivsko pole 6 str. Sofia, Bulgaria

Abstract

Electrochemotherapy is an effective method for treatment of skin tumors. To monitor the effects of application of the electrochemotherapy autofluorescence spectra are taken from the lesion and surrounding healthy skin, prior to, immediately after treatment and at the control check-ups. Patients are followed up at the first week after treatment and one month later. Here we reported the case of 82 years old woman with basal cell carcinoma, which is treated with electrochemotherapy and the effect of the treatment is verified by the optical biopsy method..

Keywords

Electrochemotherapy, Skin cancer, Basal cell carcinoma, Tumor autofluorescence.

Citation

BILIANA NIKOLOVA, EKATERINA BORISOVA, EKATERINA PEYCHEVA, LATCHEZAR AVRAMOV, IANA TSONEVA, Electrochemotherapy of skin cancer treatment results estimated by in vivo autofluorescence measurements, Optoelectronics and Advanced Materials - Rapid Communications, 10, 5-6, May-June 2016, pp.433-436 (2016).

Submitted at: March 19, 2015

Accepted at: June 9, 2016