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In vivo optical imaging with Y 2 O 2 S:Eu:Mg:Ti persistent luminescent nanoparticles

XU CAO1, YUZHU GONG1, SHOUPING ZHU1, XUANXUAN ZHANG1, XUELI CHEN1, YONGHUA ZHAN1,*

Affiliation

  1. Engineering Research Center of Molecular and Neuro Imaging of the Ministry of Education & School of Life Science and Technology, Xidian University, Xi’an, Shaanxi 710071, China

Abstract

Fluorescence imaging is widely used for in vivo imaging and has provided remarkable results. However, tissue auto fluorescence and external illumination limit the SNR and re solution. Persistent luminescent nanoparticles can emit afterglow for several minutes to hours after they are excited. Therefore persistent luminescent imaging based on these materials can circumvent tissue auto fluorescence and external illumination durin g detection and obtain images with high SNR and resolution. Y 2 O 2 S:Eu:Mg:Ti is a red persistent luminescent material, which has a highly efferent luminescence and stable chemical property. This work investigates the feasibility of Y 2 O 2 S:Eu:Mg:Ti nanoparticl es in small animal imaging of lymph node and bio distribution.

Keywords

Persistent luminescent imaging, Y 2 O 2 S:Eu:Mg:Ti nanoparticles, Fluorescence imaging.

Citation

XU CAO, YUZHU GONG, SHOUPING ZHU, XUANXUAN ZHANG, XUELI CHEN, YONGHUA ZHAN, In vivo optical imaging with Y 2 O 2 S:Eu:Mg:Ti persistent luminescent nanoparticles, Optoelectronics and Advanced Materials - Rapid Communications, 12, 7-8, July-August 2018, pp.467-471 (2018).

Submitted at: Sept. 4, 2017

Accepted at: Aug. 9, 2018