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Magnetite particle utilization for blood vessel embolization - a practical modeling

GH. IACOB1, AL. D. CIOCHINĂ1, O. BREDEŢEAN1, M. RĂCUCIU2,*

Affiliation

  1. University of Medicine and Pharmacy “Gr. T. Popa” Iaşi, Romania
  2. “Lucian Blaga” University, Faculty of Science, Dr.Ratiu Street, No.5-7, Sibiu, 550024, Romania

Abstract

Amorphous magnetic microspheres, characterized by suitable magnetic properties and biocompatibility were conducted to obdurate artificial system of blood capillary vessels under magnetic control. Experimental tests were designed aiming to observe the building of the magnetic embolus inside a thin spiral or linear tube and to determine the influence of some parameters on the efficiency of occlusions: the dimensions of magnetic microspheres (1-300 µm), the debit of the liquid (4.66 - 16.5 ml/min), the viscosity of the carrier liquid (1.007 - 7.34 cSt), the direction and the induction of the external magnetic field (340 - 600 Gs), the shape of the tube and the linear length of the deposit (5 - 50 mm). Under pre-established experimental conditions the efficiencies of occlusions were between 67 % and 97 %.

Keywords

Vessel occlusion, Magnetite microparticles, Magnetic field.

Citation

GH. IACOB, AL. D. CIOCHINĂ, O. BREDEŢEAN, M. RĂCUCIU, Magnetite particle utilization for blood vessel embolization - a practical modeling, Optoelectronics and Advanced Materials - Rapid Communications, 2, 7, July 2008, pp.446-449 (2008).

Submitted at: April 12, 2008

Accepted at: July 8, 2008