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Photophysical aspects regarding the effects of Paeonia officinalis flower extract on DNA molecule labelled with methylene blue

M. E. BARBINTA-PATRASCU1,* , N. BADEA2, C. UNGUREANU2, A. ISPAS3

Affiliation

  1. University of Bucharest, Faculty of Physics, 405 Atomistilor Street, PO Box MG-11, Bucharest-Magurele, 077125, Romania
  2. University “Politehnica” of Bucharest, Faculty of Applied Chemistry and Materials Science 1-7, Polizu Street, 011061, Bucharest, Romania
  3. Department of Prosthodontics, “Iuliu Hatieganu” University of Medicine and Pharmacy, 8 Babeş Street, Cluj-Napoca, 400012 Romania

Abstract

This paper reports in vitro studies of bio-performances of an aqueous extract of Paeonia officinalis fresh petals and its interaction with methylene blue/ deoxyribonucleic acid (MB/DNA) complex. Peony extract was characterized by spectral methods (UV-Vis absorption and FTIR-ATR spectroscopy). The phytoextract exhibited good antioxidant and antibacterial properties. Spectral investigations (UV-Vis absorption and emission spectra) on DNA stained with methylene blue as an optical probe, revealed that the peony extract replaced the dye in the biomolecule. The results could be exploited as an ecological strategy to design novel materials based on DNA and natural extracts..

Keywords

Paeonia officinalis, Antibacterial and antioxidant properties, DNA, Methylene blue, Spectral characterization.

Citation

M. E. BARBINTA-PATRASCU, N. BADEA, C. UNGUREANU, A. ISPAS, Photophysical aspects regarding the effects of Paeonia officinalis flower extract on DNA molecule labelled with methylene blue, Optoelectronics and Advanced Materials - Rapid Communications, 13, 1-2, January-February 2019, pp.131-135 (2019).

Submitted at: Dec. 19, 2018

Accepted at: Feb. 12, 2019