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L. E. VÎJAN1,*
Amphotericin B, the most known polyene macrolide antibiotics, is still used as a life saving drug (golden standard or rather drug of choice) to treat systemic fungal infections. It is known that amphotericin B interacting with cellular membranes, causes an impairment of membrane function of sensitive cells, usually leakage of cellular constituents and eventually cell death. The binding of amhotericin B to stigmasteryl-trifluoromethylphenyl-carbamate was studied using UV-Vis absorption spectroscopy.
Amphotericin B (AmB), Stigmasteryl-trifluoromethylphenyl-carbamate (Stg-CF3), Absorption UV-Vis spectroscopy.
L. E. VÎJAN, Spectroscopic study of amphotericin B - stigmasteryl trifluoromethylphenyl-carbamate interaction, Optoelectronics and Advanced Materials - Rapid Communications, 2, 12, December 2008, pp.863-866 (2008).
Submitted at: Aug. 1, 2008
Accepted at: Dec. 4, 2008
Optoelectronics and Advanced Materials - Rapid Communications
(2023): 0.5 - 2023 Journal Citation Reports (Clarivate Analytics, 2024)
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